http://www.thisisms.com/forum/stem-cell ... 16584.html
Dans ce forum on parle aussi de ce traitement en belgique: (mails les liens sont morts dommage)
http://www.thisisms.com/forum/stem-cell ... 19029.html
sinon pour d'autres chiffres:
https://www.msconnection.org/Blog/Augus ... py-Soon-Be
D'autres chiffres ici:At five years, relapse free survival was 87%, MRI event free survival 85%, EDSS score progression free survival 77%, and disease-free survival (no relapses, no new MRI lesions, and no EDSS progression) was 68%. The presence of Gadolinium enhancing lesions prior to HSCT was associated with a significantly higher degree of favorable outcome (79% exhibiting disease-free survival at five years). The study’s authors conclude that that “HSCT is a very effective treatment of inflammatory active MS and can be performed with a high degree of safety at experienced centers.” Other recent studies looking at the efficacy of HSCT have found similar results
http://www.ncbi.nlm.nih.gov/pubmed/22127896/ (étude sur 74 patients)
Traduction:RESULTS:
Two patients (2.7%) died from transplant-related causes. After 5 years, 66% of patients remained stable or improved. Among patients with a follow-up longer than 1 year, eight out of 25 subjects with a relapsing-remitting course (31%) had a 6-12 months confirmed Expanded Disability Status Scale improvement > 1 point after AHSCT as compared with one out of 36 (3%) patients with a secondary progressive disease course (p = 0.009). Among the 18 cases with a follow-up longer than 7 years, eight (44%) remained stable or had a sustained improvement while 10 (56%), after an initial period of stabilization or improvement with median duration of 3.5 years, showed a slow disability progression.
2 patients ont décédés à cause de la transplantation
Après 5 ans, 66% des patients on vu leur état se stabiliser ou s'améliorer
Parmi les patients suivis pendant plus d'un an, 8 des 25 sujets en cours de rémission ont eu des améliorations durant 6 à 12 mois supérieures à 1 point d'EDSS
Parmi les 18 cas suivi plus de 7 ans, 8 d'entre eux sont restés stables ou se sont améliorés de manière soutenue et 10 après une période de stabilisation ou amélioration d'une durée moyenne de 3 ans et demi ont accusé d'une légère progression du handicap
http://www.thelancet.com/journals/lance ... 1/abstract